Founder mutations in inherited cardiac diseases in the Netherlands

In the Netherlands, several Dutch investigators have reported their findings on founder mutations from a wide array of genetically determined cardiovascular abnormalities. Over a five-year period a series of articlesdescribing these studies were published in the Netherlands Heart Journal. They illustrate how combined efforts from different disciplines, using basic and clinical information, can lead to important advances in our knowledge of hereditary cardiovascular disease.Drs Wilde and Van Tintelen, two internationally recognised leaders in the field of genetically determined cardiovascular disease, brought these articles together in this booklet. It is not only a tribute to the importantcontribution from Dutch scientists to this field but also required reading for the clinician who wants (and should!) become better informed about recent advances in this exciting area.